The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Studies on the Purification of Prothrombin from Bovine Plasma
HIROAKI OKABEKAZUO FUJIKAWA
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1974 年 112 巻 1 号 p. 15-23

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The purification and preparation of undegraded prothrombin from bovine plasma was studied with various methods. The more simple and reproducible method for the preparation of undegraded prothrombin is reported in this paper and highly active prothrombin was obtained in good recovery by DEAE-Sephadex column chromatography following ammonium sulfate precipitation. The prothrombin thus purified showed a single band on the disc electrophoresis.

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