Abstract
The kinetics of catalase synthesis and degradation were determined in acatalasemia and normal mouse livers during recovery of catalase activity after inhibition with aminotriazole. Catalase turned over with a half life of 10.0hr in acatalasemia mice and of 19.2hr in normal mice. The rate of catalase synthesis (KS) was 0.168 (PU/mg protein/hr) in acatalasemia mice and 0.271 in normal mice. The rate of catalase degradation (KD) was 0.069 and 0.036 per hour in acatalasemia and normal mice, respectively.
