The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Evaluation of Recommended Methods for Radioisotope Red Cell Survival Studies
TATSUMI UCHIDA, SHIGEO KARIYONE, MASAHIRO MIKI, MICHIAKI SATO, KATSUHIKO FUJIMORI, KOTOKO NAKAJIMA
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キーワード: mean red cell life span, corrected 51Cr method, DF32P method
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1976 年 120 巻 3 号 p. 219-223

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Mean red cell life-span in normal subjects and in patients with various hematological disorders was examined with 51Cr and DF32P. The results with 51Cr were corrected for 51Cr elution using correction factors. The results by the two methods agreed fairly well with each other, Elution rate in various hematological disorders was 2. 3% per day or less except for the patients with extra corpuscular hemolytic agents such as autoimmune hemolytic anemia or congestive splenomegaly. It is concluded that estimates of mean red cell life-span by corrected 51Cr method are more useful and sufficient than uncorrected 51Cr or DF32P method in general hematological disorders.
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    The Tohoku Journal of Experimental Medicine (TJEM) was founded in 1920 by professors of Tohoku Imperial University, Medical School. The TJEM has been published continuously, except for the year of 1946 just after the World War II. The TJEM is open to original articles in all branches of medical sciences. The TJEM also covers the fields of disaster-prevention science, including earthquake archeology.


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