抄録
Incorporation of 3H-thyrnidine into peripheral blood lymphocytes in the presence of plasma derived from a halothane-treated donor was measured in vitro in the patient who suffered from postoperative hepatitis after second exposure to halothane. A healthy subject was also studied as a control. Lymphocytes from the patient with an active stage of hepatitis, but not from the patient after recovery from the disease, were stimulated by halothane-plasma. In the lymphocytes from a healthy subject, no responses to the same plasma was found. These results suggest that the elicitation of halothane-sensitized lymphocytes was involved in the pathogenesis of liver damage in the patient.
