抄録
MORISAKI, N., MATSUOKA, N., SAITO, Y. and KUMAGAI, A. Effects of Pantethine and Its Metabolites on Fatty Acid Oxidation in Rat Liver Mitochondria. Tohoku J. exp. Med., 1983, 141 (1), 33-39 - The mechanism of the activating effect of pantethine [D-bis-(N-pantothenyl-β-aminoethyl) disulfide] on fatty acid oxidation was investigated in rat liver mitochondria. Pantethine, pantetheine and 4'-phosphopantetheine activated three steps of fatty acid oxidation, i.e., acyl-CoA synthetase, carnitine acyltransferase and intramitochondrial oxidation, to various extents. Although their effects may have been partly due to CoASH derived from them, they also had specific effects.
