Abstract
OKUYAMA, S. Probable Binary Fission in a Reed-Sternberg Cell. Tohoku J. Exp. Med., 1991, 164 (3), 247-249 - A Reed-Sternberg cell in binary fission was observed in a case of Hodgkin's disease of nodular sclerosis type. This was thought to possibly represent a primitive eukaryotic manifestation or a retrograde replay of the endosymbiotic evolution of the modern eukaryotes as a part of devolution of malignancy (Okuyama and Mishina 1990).