Abstract
The piqûre of Cl. Bernard was performed on the non-anaesthetized dogs, the suprarenal glands of which were either extirpated with out fastening or causing any notable sensory stimulation or previously denedullated. The mean arterial blood pressure and the blood sugar concentration were followed, and the data were compared with the control experiments in which the suprarenals remained wholly uninterfered with, those in the present paper and those in the previous. 1)
Generally speaking whether or not the epinephrine secretion is interfered with has no bearing upon the blood pressure fluctuation taking place on puncturing, but great influence on the blood sugar concentration. The piqûre hyperglycaemia is definitely reduced when the suprarenals or their medullae are removed.
When the epinephrine liberation was eliminated, the piqûre also caused in most cases a definite rise of the blood pressure; the heart beat became slow. Occasionally an abrupt and transtiory fall preceded the rise of pressure; this is also observable in the control experiments.
