Studies on the Detoxicating Hormone of the Liver (Yakriton)
61st Report. Effect of Yakriton* in 1/2 R. A. U. upon Blood Picture including Nuclear Shift
1935 年 26 巻 3 号 p. 172-182
詳細
1935 年 26 巻 3 号 p. 172-182
If yakriton is subcutaneously injected in the amount of 1/2 R. A. U. per kilo of body weight into b-(low-) and f-(high-) classed rabbits, then the blood picture will change as described below:-
(1) Total white cell count. They will show a leucocytosis after the injection, reaching the maximum in the 4th or the 5th hour. The restoration of the number to normal will not always occur on the next day. At the end of one week they will show a slight leucocytosis in b-classed animals, and a slight leucopenia in f-classed ones.
(2) Lymphatic cells. They will show a decrease in number, after the injection reaching the maximum (of decrease) in the 4th hour. During the whole course of one week following the injection, they will show a lymphopenia in b-classed animals, and a lymphocytosis in f-classed ones.
(3) Myeloid cells. They will show a remarkable in crease in number, absolutely aa well as relatively, after the injection, reaching the maximum (of increase) in the 5th hour. During the course of one week following the injection, they will show a myelocytosis in b-classed animals, and a myelopenia in f-classed ones.
(4) Nuclear shift. The grade of nuclear shift will reach the maximum on the 4th or the 5th hour after the injection and will become in the b-classed two or three times, and in the f-classed three or four times more severe than before the injection. The restoration of the shift to normal will not always occur on the next day. It is to be noted here, that this shift was of a regenerative nature.
