The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
The Replacement of Epinephrine in the Suprarenals and the Splanchnic Nerves
Experiments on rabbits with physostimine
佐藤 保雄
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1938 年 32 巻 3-4 号 p. 257-267

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In order to acknowledge whether or not the interference with the innervation of the suprarenal capsule has any bearing upon the velo-city with which the epinephrine content recovers after exhaustion, rabbits were poisoned with physostigmine, and at the time when the epinephrine content was proved by other sets of experiments as highly diminished, the animals were fastened and the one side gland was de-nervated through the lumbar approach, without narcotizing. Several groups of animals were then killed, 24 hours, 48 hours, 72 hours and 96 hours after the physostigmine injection and examined for epinephrine content; by such series of experiments, not only the stage of the com-plete recovery of the storage was observed, as by a previous author, but also some intermediate stages. Whether the gland was denervated or not brought about no differences in the epinephrine content in the sister glands, one denervated, the other not. Thus we have come to the same conclusion as Crowden that the replacement of epinephrine may proceed without nervous. control.
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