The Tohoku Journal of Experimental Medicine
Online ISSN : 1349-3329
Print ISSN : 0040-8727
ISSN-L : 0040-8727
Studies on the Specific Antigens of Human Gastric Cancer. III
Katsutaro KobayashiHiroya Kawasaki
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1956 Volume 63 Issue 2-3 Pages 203-220

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Abstract

With a view to tracing the specific antigenicity of human gastric cancer a series of experiments were carried out, which essentially consisted of (1) producing antisera in rabbits by injection of saline extracts of human gastric cancer, normal gastric mucosa, and placenta, (2) preparing several purified fractions of the above three kinds of tissue, which were used as antigens for precipitin tests, and (3) performing reciprocal precipitin tests aided by reciprocal absorption tests. It has been demonstrated that the nucleic acid fraction of human gastric cancer presented the highest antigenic specificity, the glucidamin fraction a modertae, and the carbohydrate fraction least specificity.

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