Abstract
The cervical heart transplantation is a new and promising device for study of pharmacology of the denervated heart. In this experiments, pharmacological studies of vasopressants, central nervous stimulants and parasympathetic drugs on the denervated heart are studied in comparison with the recipient heart in the same body.
1. As a technique for investigating the denervated heart, the usefulness of the cervical heart transplantation described by Mann, Priestley, Marcowitz and Yater was proved.
2. Highsensitivity of the denervated heart to sympathomimetic drugs was found to be in the order of epinephrine, ephedrine and nor-adrenaline.
3. On the contrary, parasympathetics evoked no highsensitivity of the denervated heart.
4. Central nerve stimulants have no action on the denervated heart.
