Abstract
Experimental studies were carried out in dogs to investigate the interaction between succinylcholine chloride and Imbretil. The results revealed that the previous administration of Imbretil potentiated the action of succinylcholine, which was, however, antagonzied by vagostimgnine and was synergistic with d-tubocurarine. This fact suggests a possibility that Imbretil may enhance the transition of the mode of action of succinylcholine from depolarization block to non-depolarization block.
