抄録
Growth characteristics of the Sendai virus in Earle's L cell have been studied. As long as 6 hours was necessary to detect soluble antigen in the cell. Positive hemadsorption was found at 7hours. Accumulation of soluble antigen, hemagglutinin and infectious particles were detectable in this time sequence but almost from 6 to 10hours. Non-infectious heniagglutinins were first detectable inside the. cell and the release of these kinds of particles were ahead to the liberation of infectious particles. As a result, obtained harvest had the low I/A ratio, when compared to the virus population obtained after reproduction in chorioallantoic cavities of chick embryos. A kind of host-controlled variation has been observed with the particles liberated from L cells. They were infectious when inoculated into eggs but not infectious when inoculated to L cells again. They also lost the hemolytic activity which had been believed to be a dominant character of this virus, at least when grown in chick embryos.
