1962 Volume 76 Issue 4 Pages 415-419
1. Serum 5-nucleotidase determinations were made in 30 normal persons and in 111 hospitalized patients with various diseases of the liver and alimentary tract.
2. Serum 5-nucleotidase levels were found to be normal in all cases of peptic ulcer and of cancer of the gastrointestinal tract without hepatobiliary or pancreatic complications.
3. Three cases of ulcerative colitis and four of acute pancreatitis showed elevations of the enzyme in the serum.
4. Serum 5-nucleotidase elevation was frequently associated with an increase in alpha-1-globulin fraction of serum.