Abstract
1. The partially N-deacetylated preparations of sodium chondroitin sulfate A and of sodium hyaluronate were deaminated with nitrous acid.
2. The deamination products of the N-deacetylated hexosamines in these partially N-deacetylated mucopolysaccharides were shown to be hexoses and 2, 5-anhydrohexoses. The amounts of hexoses found in the non-dialyzable matters of the deamination products were more than twice as much as those of 2, 5-anhydrohexoses.
3. The experimental results indicate that the C3-substituted hexosaminidic linkages are, more or less, resistant against the deaminative cleavage to form 2, 5-anhydrohexoses with nitrous acid.
