Abstract
It is still undetermined whether tumor bearing animals produce humoral anti-tumor auto-antibodies or not. The difference of opinions about the presence of humoral anti-tumor auto-antibodies seems likely to be due to the absence of a reliable and reproducible method to detect anti-tumor auto-antibodies.
The 131I labeled antibody technique was employed in this study to detect anti-Yoshida sarcoma cell auto-antibodies in rats with subcutaneous solid Yoshida sarcoma and in rats which survived intraperitoneal injections of Yoshida sarcoma cells.
Neither sarcoma cell agglutinins nor tumor localizing auto-antibodies were demonstrated in serum of rats with subcutaneous solid Yoshida sarcoma and in rats which survived intraperitoneal inoculations of Yoshida sarcoma cells.
