An investigation was performed on the flow and cooling characteristics of highly viscous liquids in the channel with a large number of right-angled bends. The variation of flow pattern and temperature profile according to Reynolds number and Prandtl number were presented by solving numerically the Navier-Stokes equations with energy equation under the condition that the fluid properties were independent on temperature. Average heat transfer cofficient and friction factor were also calculated and compared with the experimental data regarding aqueous solutions of corn syrup. Through the comparison, the effect of the variable viscosity of the test fluid on the flow and heat transfer characteristics was considered in connection with the channel configuration.