In this paper, Cooling systems with natural circulation loop of refrigerants are reviewed. The cooling system can largely reduce energy consumption of a cooling system for the telecommunication base site. The cooling system consists of two refrigeration units; vapor compression refrigeration unit and sub-cooling unit with a natural-circulation loop. The experiments and calculations were carried out to evaluate the cycle performance of natural circulation loop with HFCs and CO2. The experimental results showed that the cooling capacity of R410A is approximately 30% larger than that of R407C at the temperature difference of 20K and the cooling capacity of CO2 was approximately 4-13% larger than that of R410A under the two-phase condition. On the other hand, the cooling capacity of CO2 was approximately 11% smaller than that of R410A under the supercritical condition. The cooling capacity took a maximum value at an amount of refrigerant and lineally increased as the temperature difference increases and the slightly increased as the height difference. The air intake temperature profile in the inlet of the heat exchangers makes the reverse circulation under the supercritical state and the driving head difference for the reverse circulation depends on the density change to temperature under the supercritical state. Also, a new fan control method to convert the reverse circulation into the normal circulation was reviewed.