抄録
The effects of several heavy metals, amines, SH-compounds and other substances upon the thiaminases obtained from the culture broth or the bacterial cells of Bacillus thiaminolyticus and Clostridium thiaminolyticum. The results obtained indicated that the intracellular enzymes were not enhanced by some kinds of metals, but by certain amines. All substances examined had the same enhancing or inhibitory effect, on both enzymes, except Fe^<..> and Cr^<..>. Enhancement by aniline, homosulfamine, pyridine, nicotinamide and cysteine was shown to a low degree. The effects of such substances on the two differnt enzymes were essentially similar, while the thiaminase of Cl. thiaminolyticum was found remarkably different from that of shell-fisches or fishes.
