抄録
When a large quantity of Aureomycin was administered to rats, the thiamine content and pyruvate oxidase of liver decreased in the early stage. The ratio of free to esterified thiamine was unchanged. FAD content and xanthine oxidase decreased from day to day. The pyruvate oxidase recovered to normal by the addition of cocarboxylase to the liver homogenate, but the addition of FAD and Mo^<++> did not cause the recovery of xanthine oxidase.