THE STABILITY OF PYRIDOXAL- AND PYRIDOXAL PHOSPHATE-SCHIFF BASES
1967 Volume 36 Issue 4 Pages 301-304
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1967 Volume 36 Issue 4 Pages 301-304
The equiliblium constants of pyridoxal- and pyridoxal phosphate-Schiff bases are determined by an optical method and the pH dependence of the Schiff bases is analysed. These results suggest that aromatic pyridoxal-Schiff bases are unstable compared with aliphatic pyridoxal-Schiff bases and the stability of pyridoxal phosphate-Schiff bases decreases at high pH value. These and the other factors affecting the stability of the Schiff bases are discuseed. These compound served as a key intermidiate in the synthesis of pyridoxal-5-phosphate.
