1969 Volume 39 Issue 2 Pages 91-96
It has been reported by several authors that the riboflavin level of tumor-bearing animal is lower than that of normal one. The present author determined the total and three types of riboflavin in liver of tumor-bearing rat. The decrease of total riboflavin to 2/3 of normal was recognized on 3-4 weeks after the plantation of tumor. A marked decrease to 1/2 of normal was found in mitochondrial fraction of liver, while in microsomal fraction it showed almost constant level through the experimental period.