抄録
The change in riboflavin metabolism of dog's salivary glands was investigated when autonomic blocking agents were administered subcutaneously. The contents of total riboflavin in the three salivary glands were found to increase at 30 minutes and to decrease than normal levels at 60 minutes after an administration of atropine. Total riboflavin content decreased in the stage of hypersecretion in parotid and submandibular gland by administration of pilocarpine, whereas it increased in the sublingual gland. Decrease of FAD and increases of FMN and free riboflavin recognized in the three salivary glands by administration of atropine. FAD fraction in the parotid increased characteristically at 30 minutes after administration of pilocarpine. From these results, the authors suggest that there is a close correlation between salivary secretion and riboflavin metabolism, furthermore, that the parotid and the submandibular glands are similar organs functionally, because of similar response was found in these organs for the administration of autonomic blocking agents.
