STUDIES ON THE EFFECT OF VITAMIN E UPON THE PRESERVATION OF BLOOD : (V) THE EFFECT OF α-TOCOPHERYLACETATE AND α-TOCOPHERYLGLYCOLATE UPON THE MORPHOLOGICAL PRESERVATION OF ERYTHROCYTES IN THE PRESERVED BLOOD

Abstract

The influence of vitamin E on the morphological preservation of erythrocytes was investigated. Normal human blood in citrate・phosphate・dextrose was diluted with its own plasma and classified microscopically into 4 types (I : biconcave disc form, II : slight crenated form, III : evident crenated form, IV : swollen, oval form). α-Tocopherylacetate was added with the concentration of 10 or 20 mg%, and in the latter case, more erythrocytes remained normal (type I) than in 10 mg% or control cases at the 7th day after sampling. No remarkable difference was existed between 10 mg% and control cases with solvent, in the respect of residual rate of normal erythrocytes. In both cases, to which α-tocopherylglycolate were added with the concentration of 20 or 50 mg% respectively, more normal erythrocytes were observed comparing with control cases with or without solvents.