抄録
Clinical observations and cooling rewarming test were made on six persons with severe acrocyanosis in the affected parts before and after administration of tocopherylnicotinate. The experimental results indicated the normal reactions in the raised limbs, and the delayed reactions in the hanging. After tocpherylnicotinate administration, above disturbances were gone and clinical appearances were also cured. Discussing the results, it was concluded that tocopherylnicotinate had the persistent and strong accelerating effects on the microcirculation of the venous side, and these effects were brought by the function which tocopherylnicotinate did not permited increasing of permeability in venous vascular wall.