Abstract
The preventive effects of tocopherol-homologues on the toxicity of oxidized oil to carp have been investigated. Carp fingering were fed with artificial diets containing oxidized ethyl ester of fatty acids prepared from pollack liver oil with or without tocopherol-homologues (see TABLE 1). Muscular dystrophy was observed in the group receiving oxidized oil without tocopherol in 60 days and the ratio or contraction amounted to 40% at the end of experiments. Such symptom, however, was effectively prevented by the addition of d-or dl-α-tocopherol whereas d-non-α- tocopherol was less effective. In the histological observation, especially of intestinal tract, the group receiving non-α-tocopherol showed excellent results on preventing intestinal tract injury. The concentration of total tocopherol of the group 3 was remarkably lower than the others, whereas the concentration of sterol of the group 6 was clearly lower than the others. From these observations, it is suggested that tocopherol-homologues may have different effects on the toxicity of oxidized oil to a living body.
