Biological Activity of 5-Chloroethylthiamine Chloride Hydrochloride : (II) BIOLOGICAL CONVERSION OF 5-CHLOROETHYLTHIAMINE TO THIAMINE IN CHICKEN (PRELIMINARY REPOT)

Abstract

Thiamine (I) and chloroethylthiamine (II) were separately estimated on thin layer chromatography by oxidatation of the compounds to their thiochrome forms. By this method, the radioactivities of ^<35>S-thiamine in chicken blood after oral administration of ^<35>S-chloroethylthiamine was counted, and it was observed that about 3% of (II) orally administered to chicken, were converted to (I).