抄録
Incorporation of pyridoxal (PAL), and its Schiff bases, oximes or 5'-acylates into red blood cells was investigated in vitro. Both influx and efflux of PAL were found to be followed by a first order kinetics, and free aldehyde group in PAL structure was essential to its rapid penetration into the cells. It was also suggested that PAL 5'-acylates (PAL 5'-n-butyrate, PAL 5'-isobutyrate, PAL 5'-benzoate) are mostly adsorbed on the cell membrane. From these findings, process of incorporation of PAL or its derivatives and their affinity to cell membrane are discussed.
