抄録
The effect of aquocobalamin (OH-B_<12>) on the oxidation of various biological materials was investigated. When catechols such as 3,4-dihydroxyphenylalanine (DOPA), pyrocatechol and adrenaline were incubated with OH-B_<12> in phosphate buffer (pH 7) under aerobic conditions at 37℃, oxygen consumption was observed. It was also found that OH-B_<12> accelerates the oxidation of linoleic acid, α-tocopherol and sulfite. In the oxidation of DOPA and linoleic acid, reaction products and reaction mechanisms were discussed.
