2005 年 79 巻 8 号 p. 383-389
Recent scientific topics on PQQ together with detouring history in its discovery, basic chemical properties, and distribution including analytical methods were reviewed. Nutritional function as to whether or not this compound is the vitamin for mammal was discussed relating to the paper recently published, in which PQQ dependent dehydrogenase might participate in the mammalian L-lysine catabolism. PQQ, which was discovered in 1979, identified as the redox cofactor for some microbial enzymes, is now deemed to be supplied from only limited microbes and supposed to be a kind of dispensable chemicals for animals. Since PQQ is one of very reactive redox compounds chemically, one might ingest this compound commonly together with other polyphenols found in plant-kingdom through human life. Critical point should be clarified first is whether or not this compound can be synthesized by green plants, because analytical data revealed that trace amount, but not negligible quantity, of PQQ was detected from vegetables and some animal products.