YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
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Aqueous Solubility of Liquid Monoterpenes at 293 K and Relationship with Calculated Log P Value
Krzysztof CAL
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2006 Volume 126 Issue 4 Pages 307-309

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Abstract

  Aqueous solubility is often a limiting factor in any concentration-dependent process and n-octanol/water partition coefficient, usually expressed as log P, is equilibrium between surrogate of nonaqueous biophases and water phase. The aqueous solubility of seven liquid monoterpenes: (±)-β-citronellol, (±)-linalool, linalyl acetate, (−)-α-pinene, (−)-β-pinene, eucalyptol and terpinen-4-ol were experimentally determined at 293 K. The obtained aqueous solubility data correlate well with log P values calculated by ACD/Log P software.

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© 2006 by the PHARMACEUTICAL SOCIETY OF JAPAN
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