YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Regular Articles
Acceptable Incremental Cost Effectiveness Ratio for Use of New Drugs, Cases in Statin Therapies
Susumu NAKAOHiroyuki KAWABEHiroki TAKUMAMakoto SHIRAGAMI
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JOURNAL FREE ACCESS

2010 Volume 130 Issue 10 Pages 1347-1352

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Abstract
  As it is an urgent issue to contain increasing healthcare expenditures, unlimited reimbursement of pharmaceuticals continues to be controversial. The objective of this study is to identify acceptable incremental cost effectiveness ratios between new and conventional therapies. Clinical study data for five statin therapies were used to indicate treatment effectiveness and incremental costs were indicated by price premiums at price listing. The incremental cost effectiveness ratios to pravastatin were 0 yen/patient with response, 1,475.1 yen/patient with response, 3,033.3 yen/patient with response, and 3,032.4 yen/patient with response. By conducting further analyses in various pharmaceuticals and categorizing acceptable incremental cost effectiveness ratios based on the disease severity and expected level of improvement in disease condition, drug prices that reflect the value of new pharmaceuticals and that are reasonable to be reimbursed can be suggested.
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© 2010 by the PHARMACEUTICAL SOCIETY OF JAPAN
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