Studies on Anti-inflammatory Agents. IV. Anti-inflammatory Constituents from Roots of Panax ginseng C.A. MEYER

Abstract

The Ginseng Radix (ginseng root) is prescribed in many Chinese medicines as a stomachic and for the purpose of antidiarrhoic effect, metabolic promotion, and hematic effects, and has been well known as one of the representative drugs of nutritious tonics. In a continuing scientific search for Chinese medicines, we tried systematic extraction of some Chinese medicines, and checked activity of each fraction by means of the fertile egg method, and found a strong inhibitory activity against the formation of granulation tissue in the chloroform extract. The detailed investigation of this extract resulted in the isolation of panaxynol (1) and linoleic acid (2), which were proved to be major active components.