YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
キャピラリー電気泳動による生薬等含有医薬品中のセンノサイドA及びセンノサイドBの定量
佐藤 かな子瀬戸 隆子宮武 ノリエ濱野 朋子塩田 寛子大西 和夫
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1999 年 119 巻 1 号 p. 88-92

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The determination of sennoside A (SA) and sennoside B (SB) by capillary zone electrophoresis was developed. The separation of SA and SB was performed in 100 mM of the 3-[cyclohexylamino]-1-propanesulfonic acid (CAPS) buffer (pH 10.0), and the migration time of SA and SB was found to be both less than 7 min. This method was applied to the analyses of seven commercial formulations containing SA and SB without previous treatment. The satistical comparison of the results obtained from both capillary electrophoresis and HPLC methods revealed an absolute correlation.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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