Pyrimidine化合體の合成研究 (第3報)

Sulfamino-pyrimidine誘導體の合成に就て その3

抄録

1) 2-Methylmercapto-4-methylpyrimidine, 2-hydroxy-4-methyl-pyrimidine hydrochloride and 2-chloro-4-methylpyrimidine were synthesized.
2) 2-Sulfanilamido-4-methylpyrimidine (Sulfamerazine) was synthesized with a good yield by the condensation of N⁴-acetyl-sulfanilamide and 2-chloro-4-methylpyrimidine under the presence of alkali carbonate.