Abstract
p-Acetylaminomethyl-benzenesulfonamide was prepared from acetylbenzylamine by sulfonation with chlorosulfonic acid and amination. From the mother liquor of the above compound, m-acetylaminomethyl-benzenesulfonamide was obtained in 5:1 ratio. On the other hand, m-aminomethyl-benzenesulfonamide hydrochloride was obtained by the reduction of m-cyanobenzenesulfonamide and was found to coincide with the compound obtained by the saponification of the above-mentioned m-acetyl compound with HCI.
o-Aminomethyl-benzenesulfonamide was obtained by the oxidation of o-toluenesulfonamide to the aldehyde and by subsequent reduction of its oxime.
