駆虫薬の研究 (第2報)

数種のCyclohexadienone類の合成

抄録

The Tiemann-Reimer reaction was utilized in the syntheses of cyclohexadienone homologs of tetraline, with 5-bromo-, 5-methyl- and 7-methyl-6-tetralol as the original material to obtain 5-bromo-, 5-methyl- and 7-methyl-6-keto-9-dichloromethyl-Δ^{7, 8⋅5, 10}, -hexahydronaphthalene, and 5-bromo-7-aldehyde-6-tetralol was obtained as the only aldehyde. As cyclohexadienone homolog of biphenyl, 4-phenyl-4-dichloromethyl-Δ^{2, 3⋅5, 6}, -cyclohexadienone was obtained together with 4-hydroxybiphenyl-3-aldehyde from 4-hydroxybiphenyl. From 4-hydroxybiphenylmethane and 4-hydroxy-4′-chlorobiphenylmethane, cyclohexadienone homologs of biphenylmethane were not obtained and only the corresponding aldehydes were found.