1951 年 71 巻 11 号 p. 1270-1272
Butyl and isoamyl bromides were respectively condensed with benzyl propyl ketone to yield α-phenylamyl propyl and α-phenyl-δ-methylamyl propyl ketones. Their oximes were reduced, led to their amines and then to acid amides, and finally submitted to isoquinoline cyclization yielding 1-(3′, 4′-methylenedioxyphenyl)-3-propyl-4-butyl- and 1-(3′, 4′-methylenedioxyphenyl)-3-propyl-4-isoamyl-3, 4-dihydroisoquinolines. The former was led to N-methyl-1, 2, 3, 4-tetrahydroisoquinoline by the usual method.