含窒素環化合物の合成 (第53報)
ピリベンザミン系抗ヒスタミン剤について (1)
1951 年 71 巻 6 号 p. 601-603
詳細
1951 年 71 巻 6 号 p. 601-603
1) By the application of dimethylamine or diethylamine on β-bromethylidene diethyl ether, dimethyl- or diethyl-aminoacetal was obtained in a good yield.
2) Grignard reagent was applied on 2-benzylideneamino- and 5-chloro-2-benzylideneamino-pyridines to form addition products which were condensed with β-dimethylaminoethyl or β-diethyaminoethyl chloride to obtain four kinds of pyribenzamine compounds.
