Benzothiazoles. VIII
Nitration of 2-Substituted Benzothiazoles
1952 年 72 巻 10 号 p. 1266-1268
詳細
1952 年 72 巻 10 号 p. 1266-1268
1) Benzothiazole, 2-methyl-, 2-methoxy-, 2-chloro-, 2-acetyl-, 2-carbethoxy-, and 2-nitrobenzothiazoles were nitrated under comparable condtions. Yield of 2-mononitro derivatives were as follows: 6-Nitro-2-methyl-, 89%, 6-nitro-2-methoxy-, 82% (including that of 2-hydroxy-6-nitrobenzothiazole); 6-nitrobenzothiazole, 62%; 6-nitro-2-chloro-, 48%; 6-nitro-2-acetyl-, 28%. From 2-nitrobenzothiazole, no nitration product was obtained.
2) In benzothiazole, 2 and 6-positions may be in para-relation to each other, at least in an activated state.
