Abstract
We synthesized methyl-bis-β-chloroethylamine N-oxide and found that its effect upon the Yoshida ascites sarcoma is far more surpassing than methyl-bis-β-chloroethylamine (HN2). We also recognized that it changes in its aqueous solution (pH 8) to N-β-chloroethyl-dimethylene-1, 2-oxaimine-N-methochloride within several hours at a room temperature and then secondarily to N, N-methyl-β-chloroethyl-O-β-chloroethylhydroxylamine.
