抄録
1) Nine derivatives of bis (naphthylazophenyl) sulfone were synthesized, all of which, except one, are unknown substances in literature, and their properties have been made clear.
2) As a result of antibacterial tests, bis [p-(1-amino-4-sulfo-2-naphthylazo) phenyl] sulf one and bis [p-(1-amino-4-selfamyl-2-naphthylazo) phenyl] sulfone, were found to possess effects similar to that of sulfanilamide.
3) As for antiviral effects, the 2 said compounds were also found effective on the virus. It is of interest that these 2 compounds showed considerable activities against both bacteria and viruses.
4) Antibacterial and antiviral properties of derivatives of naphthalene sulf onic acid hitherto synthesized were reviewed, and it was found that many compounds of this series possessed antiviral activitis more marked than that of naphthionic acid, and it was also concluded that derivatives of bis (naphthylazophenyl) sulfone might be of promise for a wide range of microbial diseases.
5) It seems possible to obtain, by syntheses, more effective antiviral drugs in future, judging from the fact that compounds possessing antiviral activities were found by these studies.
