1-フェニル-2-ヂメチルアミノプロパンの光学異性体の合成
1952 年 72 巻 9 号 p. 1096-1098
詳細
1952 年 72 巻 9 号 p. 1096-1098
By the high pressure catalytic reduction of phenylacetone and dimethylamine, with a nickel catalyst, dl-1-phenyl-2-dimethylaminopropane was obtained in 58% yield. This was resolved into optical isomers, using tartaric acid, to d-1-phenyl-2-dimethylaminopropane hydrochloride, m. p. 182-183°, [α]D16+13.1°, and l-compound, m. p. 182-183°, [α]D16-13.1°.
