有機定性分析 (第3報)
N-ジエチルグリシンヒドラチッドによるカルボニル化合物の分離及び定性
1953 年 73 巻 2 号 p. 105-106
詳細
1953 年 73 巻 2 号 p. 105-106
N-Diethylglycine hydrazide, b.p.2 105°, was prepared by the reaction of N-diethyl-glycine ethyl ester and hydrazine hydrate. The hydrazide gave a sulfate of m.p.118° as recrystallized from alcohol, which is not hygroscopic and is stable in the air. For the general isolation of carbonyl compounds from a mixture, N-diethylglycine hydrazide is applied to the mixture in acetic acid acidity, the reaction mixture shaken with ether to remove substances other than carbonyl compounds, and the aqueous solution is alkalized with sodium bicarbonate by which the carbonyl compound precipitates out as the hydra-zone. To regenerate the carbonyl compound, the hydrazone is dissolved in 1N hydrochloric acid, the mixture allowed to stand for 12-24 hours, and the carbonyl compound is liberated.
