抄録
A system for the quantitative determination of isonicotinic acid hydrazide and its decomposition product, isonicotinic acid, in various body organs was established. Using a cat, physiological distribution of INAH was examined and it was found that INAH was absorbed rapidly but that the decomposition did not occur to a great extent. In a perfusion experiment using cat liver, the manner of fixation of INAH in liver became clear and it was assumed that the toxicity of INAH was not the toxicity of INAH itself but of a substance formed from it. It is hoped that further studies may be made on this substance.
