1954 年 74 巻 5 号 p. 488-489
Paper electrophoresis was utilized for the detection of substances giving positive Jaffé reaction, and creatine and creatinine were separately detected by simple procedures. This method was applied for the urine analysis of normal persons in pregnancy, and in patients suffering from Banti's disease, uterine carcinoma, pernecious anemia, cachexia, and chlio epithelioma. Urine from such persons contained a fair amount of substance giving positive Jaffé reaction, besides creatine and creatinine, and the tendency was especially marked in the case with pernecious anemia. The separation of creatine and glycothiamine, and of creatinine and glycothiamidine was found difficult.