Vitamin B1関係化合物の研究 (第14報)
ケトカルボン酸エステルのdithiocarbamateについて
1954 年 74 巻 6 号 p. 602-605
詳細
1954 年 74 巻 6 号 p. 602-605
Reaction of benzylamine or 2-methyl-4-amino-5-aminomethylpyrimidine, carbon disulfide, and α- or β-haloketocarboxylic ester respectively yielded N-substituted 4-hydroxythiazolidine-2-thione (IV), (XVII), and (XXIII). The objective compound could not be obtained in the case of α-alkyl-α-haloketocarboxylic ester. The reaction of dimethylamine, α-haloketocarboxylic ester, and carbon disulfide gave N-substituted dithiocarbamate (VII). (IV) does not give any coloration with ferric chloride but (VII) gives a blue violet coloration, from which the structure of (IV) was confirmed.
