Diphenyl Etherを基核とする数種のThiazole誘導体の合成 (第1報)
1954 年 74 巻 8 号 p. 850-853
詳細
1954 年 74 巻 8 号 p. 850-853
In order to test the antibacterial action of thiazole derivatives, 6 kinds with diphenyl ether as the basic nucleus and 2 with diphenyl sulfide as the basic nucleus, shown in Table I, were synthesized. Growth inhibition tests in vitro with human type tubercle bacilli (H37 Rv) showed that the compound (V) alone possessed a strong antibacterial action while 7 other allied compounds showed only a weak action. All the 8 compounds tested also showed only a weak antibacterial action against other bacteria, such as Bacillus dysentereae and Salmonella typhosa.
