1955 年 75 巻 6 号 p. 645-648
2-Substituted and 2, 3-disubstituted arylthio-1, 4-naphthoquinones listed in Table I were prepared and their antibacterial action was examined (cf. Table II). The antibacterial mechanism of the naphthoquinones has been explained as their bonding with SH compounds, necessary for bacterial growth, but some of their derivatives containing a substituted SH group also showed bacterial action. It was therefore pointed out that the bacterial growth may possibly be inhibited by the oxidative mechanism in oxidoreduction potential of the quinoid structure which changes with the substituent present, as a more important factor of the antibacterial action of the naphthoquinones.