抄録
6-Iodo-3-aminohydrocarbostyril (II) was prepared from 3-acetaminohydrocarbostyril by the application of iodine monochloride to its glacial acetic acid solution to form (I) which was deacetylated with dilute hydriodic acid. The position of the iodine in (II) was confirmed by oxidation with potassium permanganate followed by boiling with N sodium hydroxide to 5-iodoanthranilic acid. Administration of the aqueous solution of the hydrochloride of (II) to mice showed that it possessed the pharmacodynamic action of amyostatic poison, almost similar to that of 3-aminohydrocarbostyril.
